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Clinical trial evaluating potential treatment for postpartum depression

Currently, there are no drugs specifically indicated to treat postpartum depression, which affects an estimated 10 to 20 percent of all mothers who give birth, according to Samantha Meltzer-Brody, M.D., M.P.H., director of the Perinatal Psychiatry Program at the UNC School of Medicine, and academic principal investigator and senior author of the study published in  The Lancet . Steve Kanes, M.D. Ph.D., Chief Medical Officer of Sage Therapeutics , is the lead author of the paper. Postpartum depression is a mood disorder in women that can be triggered in some women by fluctuations in reproductive hormones. Common symptoms in mothers that experience PPD include low mood, feeling overwhelmed, anxious and ruminating thoughts, potential withdrawal from the baby and her family, and, in the most severe cases, suicidal thoughts. "The results of this trial are like nothing I've seen before in the treatment of postpartum depression," Meltzer-Brody said. "It's vital th...

People who are 'phone snubbed' by others often turn to their own phones, social media for acceptance, study finds

Building on their earlier study that phubbing can damage relationships and lead to depression, researchers Meredith David, Ph.D., assistant professor of marketing, and James A. Roberts, Ph.D., The Ben H. Williams Professor of Marketing, have found that the circle nearly completes itself as the offended parties frequently jump online to find affirmation in the likes and shares and positive comments of social media. Their study, "Phubbed and Alone: Phone Snubbing, Social Exclusion, and Attachment to Social Media," is published in the  Journal of the Association for Consumer Research . The research investigates the relationship between phubbing, social media attachment, depression , anxiety and stress. "When an individual is phubbed, he/she feels socially excluded which leads to an increased need for attention. Instead of turning to face-to-face interaction to restore a sense of inclusion, study participants turned to social media to regain a sense of belonging,...

State medical licensing boards' practices may hurt physician mental health

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A brand new examine discovered state medical boards ask physicians rather more in depth and intrusive questions on psychological well being situations than for bodily well being situations. Credit score: Michigan Drugs Sharing a historical past of psychological well being points with an employer is tough for anybody. It is that a lot more durable if reporting an previous or well-controlled situation might result in restrictions in your skilled license -- as some physicians properly know. A brand new examine discovered state medical boards ask physicians rather more in depth and intrusive questions on psychological well being situations than for bodily well being situations. Regardless of nationwide concern about doctor suicide and well-being, analysis exhibits that even when physicians wrestle with despair, they're reluctant to reveal and search therapy as a result of it might have severe penalties once they apply for his or her medical license. Katheri...

Early stress confers lifelong vulnerability causing alterations in a specific brain region

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Earlier research have urged that adolescence stress will increase the chance for despair and different psychiatric syndromes, however the neurobiology linking the 2 has remained elusive till now. Credit score: © fuzzbones / Fotolia Youth stress encodes lifelong susceptibility to emphasize via long-lasting transcriptional programming in a mind reward area implicated in temper and despair, in line with a research carried out on the Icahn College of Drugs at Mount Sinai and printed June 15 within the journal  Science . The Mount Sinai research focuses on epigenetics, the research of modifications within the motion of genes brought about not by modifications in DNA code we inherit from our mother and father, however as an alternative by molecules that regulate when, the place, and to what diploma our genetic materials is activated. Such regulation derives, partly, from the perform of transcription components -- specialised proteins that bind to particular DN...

Meditation and yoga can 'reverse' DNA reactions which cause stress, new study suggests

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A brand new research examines the deep advantages of meditation and yoga. Credit score: © frankie's / Fotolia Thoughts-body interventions (MBIs) comparable to meditation, yoga and Tai Chi do not merely calm down us; they'll 'reverse' the molecular reactions in our DNA which trigger ill-health and despair, in accordance with a research by the colleges of Coventry and Radboud. The analysis, printed within the journal  Frontiers in Immunology , critiques over a decade of research analysing how the behaviour of our genes is affected by completely different MBIs together with mindfulness and yoga. Specialists from the colleges conclude that, when examined collectively, the 18 research -- that includes 846 contributors over 11 years -- reveal a sample within the molecular modifications which occur to the physique on account of MBIs, and the way these modifications profit our psychological and bodily well being. The researchers give attention to how ...

Cognitive behavior therapy significantly reduced depression and anxiety in chronic pain patients

This treatment also resulted in significant increases in self-efficacy, activity engagement and pain acceptance. To assess the potential benefits of an 8-week programme of group Acceptance and Commitment Therapy ( ACT ) in people with persistent pain, measures of pain acceptance and activity engagement were taken using the Chronic Pain Acceptance Questionnaire. Measures of psychological distress using the Hospital Anxiety and Depression Scale and self-efficacy were also taken at assessment, on the final day of the programme, and at the follow up six-month review. For those chronic pain patients with scores at all three time points, there were statistically significant improvements in all parameters between baseline and at six-months follow-up, including the change in mean score of depression, anxiety, self-efficacy, activity engagement and pain willingness (p<0.001). "To further validate the role of ACT in the treatment of chronic pain, specifically in a rheumatology co...

Depressed patients more likely to be prescribed opioids

"Our findings show that these drugs are more often prescribed to low back pain patients who also have symptoms of depression and there is strong evidence that depressed patients are at greater risk for misuse and overdose of opioids," said John Markman, M.D., director of the Department of Neurosurgery's Translational Pain Research Program at the University of Rochester Medical Center (URMC) and senior author of the study which appears in  PAIN Reports , a journal of the International Association for the Study of Pain. Low back pain is a leading cause of disability in the U.S., the most common condition for which opioids are a prescribed treatment. Using data from the Medical Expenditure Panel Survey, a federally-compiled set of large-scale surveys of families and individuals, their medical providers, and employers across the U.S., the researchers compiled opioid prescription data from 2004-2009. This period is important because it coincides with a steep rise the pre...